CBD is a phytocannabinoid; a cannabinoid of plant origin. This is opposed to an endo-cannabinoid, which is one formed endogenously (by your own body). A cannabinoid is a type of compound that interacts with the endocannabinoid system, a large collection of nerves in your body that are responsible for regulating mood, hunger, sleep cycles, and more. THC is also a cannabinoid, but one with psycho-active effects that result in a ‘high’. CBD doesn’t get you high. Instead, CBD inhibits action on the CB1 receptors in your brain, which is the mechanism by which THC gets you high. Rather than stimulating your endo-cannabinoid system, it helps to calm it (and you) down. CBD acts indirectly on the endo-cannabinoid system through complex and varied mechanisms, which makes its effects gentle.
CBD’s most profound effect is in reducing inflammation. Inflammation is either the primary cause or a secondary effect of most ailments. Inflammation is caused by pro-inflammatory enzymes called cytokines. CBD has been shown to stop these enzymes and therefore diminish inflammation. Inflammation can cause a number of ailments such as rheumatoid arthritis, multiple sclerosis, and fibromyalgia; because CBD treats the root cause of these ailments, it is particularly effective . Cranial inflammation is believed to be the cause of certain cognitive issues such as anxiety, brain fog, and mood swings; CBD effectively alleviates these ailments by reducing inflammation in the brain.
None have been discovered yet. CBD shows extremely low risk of toxicity, making it safer than traditional NSAIDs and just about all pharmaceuticals. CBD has shown to markedly improve the effects of chemotherapy and pain management medicine.
CBD is bio-synthesized by the hemp plant, meaning it grows naturally from hemp. All cannabinoids come from resin glands in the flowering buds of the plant. These glands secrete the cannabinoids and terpenes in the form of trichomes, or the crystals that cover the outside of buds.
These are all different words for cannabis, essentially. These words were created by the government for a variety of purposes. Everything in the genus is cannabis. The term ‘marijuana’ was created in the 50s to tap into the fear of mexican immigrants and their drugs. Since then, the government has changed the terms to give them more legally rigorous definitions. ‘Cannabis’ or ‘marijuana’ is used to denote cannabis plants that contain high THC content, which is defined as >.3% of the dry weight. ‘Hemp’ was chosen to distinguish strains which contain less than .3% THC, usually containing higher amounts of CBD or other cannabinoids instead.
Strains of cannabis were groomed to be “hemp” by selective breeding. Strains that had minimal amounts of THC were interbred until we achieved high amounts of CBD with low THC. Just like tomatoes or corn, we take these plants and breed them to have the qualities we would prefer. For a long time, farmers only selected strains that were high in THC. Now that the benefits of CBD are becoming better understood, today’s sought-after strains are high in CBD.
In most cases, a cold ethanol extraction is the first step. Flower or biomass is immersed in ethanol at -30C. The cold prevents unwanted plant matter from being dissolved into the cannabinoids that we are extracting. After the ethanol extraction, you get dark brown raw extract called crude oil. This is then distilled further through a variety of methods. The most basic setup is called a short path, a type of fractional distillation where the resin is evaporated and distilled. There are also various “molecular distillation” methods, such as a wiped film evaporator. This is where the purity can go up to ~90%. In order to completely remove the THC, something called flash column chromatography is often used. Centrifugal partition chromatography can be used for higher speed and efficiency. These require harsher solvents that are later removed.
The endocannabinoid system is the largest collection of nerves in the human body. It is responsible for maintaining homeostasis, which is the balance of the body’s regulatory functions. Endocannabinoids (eCBs) and their receptors are found throughout the human body: nervous system, internal organs, connective tissues, glands, and immune cells. It contains a highly varied array of signalling pathways. It modulates physiological factors related to everything from cognition to the immune system. The broad impact of these systems affects hunger, digestion, anxiety, pain, stress, inflammation, and more. You’d be hard pressed to find a physiological function not regulated directly or impacted by the function of your endo-cannabinoid system.
The endocannabinoid system contains two main receptor sites CB(1) and CB(2). Two endogenous cannabinoids that act as neurotransmitters are: N-arachidonoylethanolamine (AEA or Anandamide for short) and 2-arachidonoylglycerol (2-AG).
CBD calms your endocannabinoid system by regulating the stimulation of the CB1 receptor. As THC stimulates the CB1 receptor, CBD will modulate that action and inhibit the anxiety THC can cause.
Alongside cannabinoids, hemp contains compounds known as terpenes. Terpenes are responsible for the characteristic scent/flavor of cannabis. Terpenes can also offer a range of health benefits. For example, beta-caryophyllene is a terpene in our tinctures that engages with the endocannabinoid system in a similar manner to cannabinoids.
About the Remedy
The Remedy is a place where people can come to learn about CBD and other cannabinoids through experience and high quality information. Alex started this company with a focus on making concentrated and effective products. Through meticulous research, our products are formulated with ingredients that maximize endocannabinoid stimulation and steer the effects of CBD towards more specific purposes. Together, the store and brand represent unparalleled quality and integrity.
We create all of our products ourselves from scratch. Most companies get their products white labeled by one of 5 manufacturers, making their product generic. Most products are just CBD emulsified in an oil, diluted to a dosage they have decided is appropriate. Many of those companies arbitrarily created those dosages to hit certain price points or because that was what the manufacturer offered. Many times those dosages are lacking, as is information on what quality or type of extract is being used in those formulations. Hopefully, the reselling company will have that information, but they are often focused exclusively on branding. There is more to a good product than a clean lab report and nice packaging. The difference is: our products are made solely to be as effective as possible. As many active ingredients are packed into whatever the form factor of the product allows. We utilize every type of CBD extract for various products that accentuate the benefits of that extract. No extract is superior, but they all have benefits and drawbacks; we are happy to share our knowledge and personal experience so you can decide for yourselves.
Our products include cannabimimetic (i.e. compounds that engage with the endocannabinoid system despite not being cannabinoids) and endocannabinoid reuptake inhibiting natural ingredients that add delicious flavor and compound the effect of our CBD. This makes our products work faster and more efficiently so you get more benefit per mg and thus more benefit for your money.
We are constantly creating new and beneficial products. We listen to our customers and adapt. MCT oil upset just a few of our customers’s stomachs, so we switched to hemp oil, and now finally olive oil for maximum antioxidant and anti-inflammatory effect and without refinement. Soy lecithin was an allergen to some, so we switched to sunflower lecithin. We do everything we can to better serve and accommodate our customers. Nothing makes us happier than to see another chronic symptom be relieved for the first time.
No we are not, and we are proud of that. Our doors are open to all, no need for license or extra fees. We do not agree with the medical system in Connecticut. The dispensaries are overpriced due to state taxation and monopoly price gouging. The owner Alex, let his medical card expire; to him, the sub-par quality products were not worth the yearly $300 renewal fee.
The medical program forces you to buy from only one dispensary. We welcome everyone; no license is necessary and you can shop at any store you like. Our products are more affordable per active mg compared to the dispensary. The medical products are also not made creatively or effectively; they typically only extract from the cannabis plant and combine with essential oils, even in vape products. The dispensary formulations are not nearly as robust as ours. Dispensaries’s cannabis is also forced to grow in a nearly microbe free environment, which is not natural or beneficial for the plant. A grower we know and respect turned down a job at AGL because he refused to grow under these conditions.
Finally, the dispensary will tell you to smoke THC in order to sleep better. THC blocks users from entering their REM sleep cycle and therefore prevents a deep restful sleep. If the dispensaries are unaware of this, then they aren’t knowledgeable enough to sell these products to you. If they are aware, then they are prioritizing their sales before your health. In a similar vein, they label products and strains as indica and sativa with alleged authority but fail to inform users that these genetics have been largely bred out of existence. There are mostly only hybrids now, which do not have the coveted genetics of the pure bred original strain. They typically have someone sitting in a sampling room trying strains and deciding, based entirely on their opinion, which it is. The distinction is, in effect, completely fabricated. They don’t tell you this because it undermines their authority.
At The Remedy, we will never lie, mislead, or pretend to know anything we don’t. We will inform to the extent that is currently known, and are happy to inform users about the limits of modern research and understanding.
We work with labs all over the country, primarily in Oregon and Colorado. These are the places that have been doing it the longest and have the largest established laboratories. These well-equipped labs are able to produce consistent and high quality extracts we need to make the formulations you love. We actually use a different extract for almost every product type, as we’ve found even minute differences in the types of extract used can have substantial benefits depending on the type of product.
We source everything we can locally, which until recently wasn’t possible. Now that hemp laws are becoming less restrictive, we can finally get locally sourced hemp. We help farms in Connecticut get started and partner with them, and are proud to offer their flower in our stores. We scour the area for the best quality hemp and offer a curated selection of CBD flower. We use distilled CBD from a local distillation lab when we can.
CBD products are usually such a low percentage CBD that it is not the ideal metric to use to gauge the amount of CBD you’ll actually be getting. For higher concentration products such as vape cartridges or concentrates, percentages makes more sense. For example, 1g of crystallite is 85% CBD, meaning it contains 850mg of CBD. With products such as topicals, it’s not so clear cut. For example, let’s say we have a product that is 500 mg in a 4oz container, which equates to .4% CBD. That .4% figure is not very informative with regard to practical use. We designate our products by the amount of CBD in mg. On our website, we illustrate the breakdown of how many mg are in each mL, which is useful information to the average consumer. 1mL or even .5mL is a realistic usage of a topical product, so it is helpful to know how much CBD you might actually utilize. This figure also helps to compare potencies with other brands more easily, as most brands list CBDmg and total volume (mL).
We do not and we never will, nor will anyone else. High quality cartridges are made in .5 or 1mL sizes, we will always provide 1mL to give you the most for your money and reduce plastic waste. Companies often claim 1000mg on the package of a 1mL cartridge. This leaves people confused because that 1000mg would usually imply the amount of CBD. In reality, the only thing that number could be related to is an approximation of the total volume of the cartridge. CBD is also hard to keep stable as an oil in high concentrations. 1000mg in a vape cartridge would have to be isolate (a white powder), and it would technically be 999mg or 989mg depending on the potency. In short, 1000mg of CBD is never going to fit in a vape cartridge.
Once an oil is above 60% CBD, it becomes destabilized. When this happens, the CBD is more and more likely to “crash out” or precipitate from the solution. We have always pushed out vape carts to be as potent as possible. This means that a change of conditions may allow the CBD to separate from the terps and other natural oils in the extract. This is totally normal and natural; the heat from the cartridge will usually melt it all back into a homogenous solution. If this is not enough to fix it, try warming gently with a heat gun or hair dryer.
Batteries are turned on by 5 swift clicks to the round button. The light will flash when turned on. Do the same to turn it off.
Turn the dial on the bottom to adjust voltage. We usually recommend between 3.8v-4.2v.
What is most important to look at when comparing any CBD product is the mg/mL or milligram per volume. Our topicals have a high amount of CBD per the total volume. We keep our volumes small so that each application of CBD is a medicinally effective dose. Many companies will have
1000mg cream or lotion but often in a 8oz bottle. 8 ounces is 224mL and that means the 1000mg is spread very thinly, 4.4mg per mL to be exact. Our soothing butter only has 300mg of CBD but that is in one ounce, that is 10.7mg per mL more than twice as potent as the former example. Not only do our topicals contain high concentrations of CBD but they also include a multitude of other beneficial ingredients that work synergistically with the cannabinoids. This means that each mg of our product will have a far greater effect than that of a product that is simply CBD alone.